This collection of original essays explores the connections between the philosophies of Alfred North Whitehead and the classical American pragmatists.

In what follows our purpose is to make clear the reasons which lie back of Whitehead's appeal to eternal objects in his explanation of the emergence of actual entities and to show that so long as one operates within his scheme of ideas no other consistent explanation is available. A thoroughgoing reconstruction of the scheme is necessary if this presupposition is to be eliminated. If the project is successful, it will be demonstrated that the theory of actual entities provides no (...) basis for the explanation of the emergence of novel things, which is one of the major tenets of the organic philosophy. The argument will develop by way of an analysis of the theory of “physical relatedness.”. (shrink)

The most satisfactory way of isolating the specific issues with which this paper is concerned is by way of a brief summary of the theory and its internal development. The development of the theory embodies two major movements. These are: an analysis of what the author considers the typical perceptual experience, “a perceptual situation”, and the projection of a theory of the physical world on the basis of the results derived. We may consider these in order.

The most direct manner of formulating the objective of this paper is to consider some passages in which Whitehead states the conception of the “subject” espoused by the organic philosophy.“The subjectivist principle is that the whole universe consists of elements disclosed in the analysis of the experiences of subjects.” “The reformed subjectivist principle adopted by the philosophy of organism...” is “... that apart from the experiences of subjects there is nothing, nothing, nothing, bare nothingness.”.

Die Welt ist voller Leid. Gott ist entweder unfähig, es zu verhindern – dann ist Er nicht allmächtig –, oder Er will es nicht verhindern – dann ist Er nicht vollkommen gut. Seit Generationen wird dies als das schlagendste Argument gegen den Glauben angesehen, daß ein allmächtiges und allgütiges Wesen existiert. Natürlich haben Theisten sich die größte Mühe gegeben, eine angemessene Erwiderung vorzubringen. ... Selbst wenn nur ein einziges Individuum unnötigerweise für einen kurzen Moment eine leichte Unannehmlichkeit zu ertragen hätte, (...) wäre das Problem logisch ebenso real – obwohl es nicht so schmerzhaft wäre oder möglicherweise sogar unbemerkt bliebe. (shrink)

Neuroenhancement involves the use of neurotechnologies to improve cognitive, affective or behavioural functioning, where these are not judged to be clinically impaired. Questions about enhancement have become one of the key topics of neuroethics over the past decade. The current study draws on in-depth public engagement activities in ten European countries giving a bottom-up perspective on the ethics and desirability of enhancement. This informed the design of an online contrastive vignette experiment that was administered to representative samples of 1000 respondents (...) in the ten countries and the United States. The experiment investigated how the gender of the protagonist, his or her level of performance, the efficacy of the enhancer and the mode of enhancement affected support for neuroenhancement in both educational and employment contexts. Of these, higher efficacy and lower performance were found to increase willingness to support enhancement. A series of commonly articulated claims about the individual and societal dimensions of neuroenhancement were derived from the public engagement activities. Underlying these claims, multivariate analysis identified two social values. The Societal/Protective highlights counter normative consequences and opposes the use enhancers. The Individual/Proactionary highlights opportunities and supports use. For most respondents these values are not mutually exclusive. This suggests that for many neuroenhancement is viewed simultaneously as a source of both promise and concern. (shrink)

Sex steroids, through their receptors, have potent effects on the signal pathways involved in osteogenic or myogenic differentiation. However, a considerable segment of those signal pathways has a prominent role in epithelial neoplastic transformation. The capability to intervene locally has focused on specific ligands for the receptors. Nevertheless, many signals are mapped to interactions of steroid receptor motifs with heterologous regulatory proteins. Some of those proteins interact with the glucocorticoid receptor and other factors essential to cell fate. Interactions of steroid (...) receptor domain motifs with heterologous proteins affect specific target pathways; consequently, manipulation of specified protein modules complexed with steroid receptors may be a next major step for enhancing molecular targeted therapeutics. In the future, intervention at specific sections of receptor primary sequence may prove therapeutically more efficient in targeting pathways of choice than ligand selectivity can be. (shrink)

ObjectiveOverweight and obesity [body mass index ≥ 25 kg/m2] are associated with poorer prognosis among women with breast cancer, and weight gain is common during treatment. Symptoms of depression and anxiety are also highly prevalent in women with breast cancer and may be exacerbated by post-diagnosis weight gain. Altered brain function may underlie psychological distress. Thus, this secondary analysis examined the relationship between BMI, psychological health, and resting state functional connectivity among women with breast cancer.MethodsThe sample included 34 post-menopausal women (...) newly diagnosed with Stage 0-IIa breast cancer who were enrolled in a 6-month randomized controlled trial of aerobic exercise vs. usual care. At baseline prior to randomization, whole-brain analyses were conducted to evaluate the relationship between BMI and seed-to-voxel rsFC of the hippocampus and amygdala. Connectivity values from significant clusters were then extracted and examined as predictors of self-reported depression and anxiety.ResultsMean BMI was in the obese range. For both seeds examined, higher BMI was associated with lower rsFC with regions of prefrontal cortex, including ventrolateral PFC, dorsolateral PFC, and superior frontal gyrus. Hippocampal connectivity with the vlPFC was negatively correlated with self-reported anxiety.ConclusionHigher BMI was associated with lower hippocampal and amygdala connectivity to regions of PFC implicated in cognitive control and emotion regulation. BMI-related differences in hippocampal and amygdala connectivity following a recent breast cancer diagnosis may relate to future worsening of psychological functioning during treatment and remission. Additional longitudinal research exploring this hypothesis is warranted. (shrink)

Neuroenhancement involves the use of neurotechnologies to improve cognitive, affective or behavioural functioning, where these are not judged to be clinically impaired. Questions about enhancement have become one of the key topics of neuroethics over the past decade. The current study draws on in-depth public engagement activities in ten European countries giving a bottom-up perspective on the ethics and desirability of enhancement. This informed the design of an online contrastive vignette experiment that was administered to representative samples of 1000 respondents (...) in the ten countries and the United States. The experiment investigated how the gender of the protagonist, his or her level of performance, the efficacy of the enhancer and the mode of enhancement affected support for neuroenhancement in both educational and employment contexts. Of these, higher efficacy and lower performance were found to increase willingness to support enhancement. A series of commonly articulated claims about the individual and societal dimensions of neuroenhancement were derived from the public engagement activities. Underlying these claims, multivariate analysis identified two social values. The Societal/protective highlights counter normative consequences and opposes the use enhancers. The Individual/proactionary highlights opportunities and supports use. For most respondents these values are not mutually exclusive. This suggests that for many neuroenhancement is viewed simultaneously as a source of both promise and concern. (shrink)

In this paper we inquire into the fundamental assumptions that underpin the ideal of the Bio-Based Economy as it is currently developed . By interpreting the BBE from the philosophical perspective on economy developed by Georges Bataille, we demonstrate how the BBE is fully premised on a thinking of scarcity. As a result, the BBE exclusively frames economic problems in terms of efficient production, endeavoring to exclude a thinking of abundance and wastefulness. Our hypothesis is that this not only entails (...) a number of internal tensions and inconsistencies with regard to the ideal of BBE, but ultimately undermines the ideal itself, by pushing purported regenerativity into a cataclysmic and terminal discharge. We here point to the strategies that the BBE employs in this exclusion, the fundamental assumptions regarding the relation between energy and economy that underpin this endeavor, as well as to the resulting inconsistencies and their catastrophic consequences. We finally argue for the introduction of the presently excluded question of abundance and wastefulness and explore the implications of such a question for the ideal of a zero-waste humanity. (shrink)

Chemistry deserves more philosophical attention not so much to do justice to a long-neglected science or to enhance its cultural prestige, but to undermine a number of taken-for-granted assumptions about scientific rationality and more importantly to diversify our metaphysical views of nature and reality. In brief, this paper does not make the case for a philosophy of chemistry. It rather urges philosophers of science to listen to chemists and discuss what they learn from them. Because over the course of many (...) centuries chemists have developed a special access to nature and a special way of investigating and dealing with material substances, they have confronted a number of epistemological and ontological issues that are worth discussing. Following critical remarks about the disciplinary partition of philosophy, a historical section presents the contributions to philosophy of a few French twentieth-century chemists-turned philosophers to emphasize how they have challenged the dominant philosophical categories. The final section develops one of the lessons that philosophers can learn from chemists: to pay attention to things, to their materiality and activity in order to develop new ontological perspectives. (shrink)

Le présent article a pour but de montrer que la notion de chance , héritée d’Héraclite, revêt une place et une fonction fondamentales, architectoniques, dans l’ensemble de la pensée et de l’œuvre de Bataille. Symptôme en quelque sorte de son post-hégélianisme, elle permet de rendre compte de certaines des décisions ontologiques, anthropologiques mais aussi poétiques les plus singulières de Bataille, désormais en marge de Hegel et de Nietzsche.

La 4e de couv. porte : "Le capitalisme est une totalité qui produit des effets dans toutes les sphères de la vie. Le concept de réification, élaboré par Georg Lukács pour désigner « le fait qu’un rapport, une relation entre personnes, prend le caractère d’une chose », permet d’en rendre compte et de critiquer la réduction des individus à de simples fonctions de la reproduction sociale, ainsi que la domination qu’y exercent la marchandise, la division du travail, l’État, le droit (...) formel et la bureaucratie, sur les pratiques et les formes de vie. La Réification réunit les contributions de philosophes qui interrogent l’histoire et l’actualité de ce concept dans la perspective d’une critique du capitalisme contemporain. Y sont expliquées, discutées et réactualisées les théories de la réification à l’œuvre dans les marxismes et les théories sociales critiques, depuis Marx, Weber et Lukács jusqu’à Adorno, Lefebvre, Sartre, Honneth, Žižek et les théories queer et féministes. Cet ouvrage collectif, en montrant au-delà des théories philosophiques et sociologiques habituelles que le capitalisme est une forme sociale totale, porte un éclairage original dans les débats contemporains sur le capitalisme et son dépassement.". (shrink)

This paper offers a twofold ontological conceptualization of technology in the Anthropocene. On the one hand, we aim to show how the Anthropocene occasions an experience of our inescapable inclusion in the technological structuring of reality that Martin Heidegger associates with cybernetics. On the other hand, by confronting Heidegger’s thought on technology with Georges Bataille’s consideration of technological existence as economic and averted existence, we will criticize Heidegger’s account by arguing that notwithstanding its inescapable inclusion in cybernetics, technology in the (...) Anthropocene itself fosters an experience of what remains excluded. We conclude by indicating how such an experience is relevant for contemporary philosophical investigation of technology. (shrink)

This collection of thirteen essays, when viewed together, offers a unique perspective on the history of American philosophy. It illuminates for the first time in book form, how thirteen major American philosophical thinkers viewed a problem of special interest in the American philosophical tradition: the relationship between experience and reflection. Written by well-known authorities on the figure about which he or she writes, the essays are arranged chronologically to highlight the changes and developments in thought from Puritanism to Pragmatism to (...) Process Philosophy. While Doctrine and Experience will be of particular interest to specialists in American Philosophy, there is also much to offer anyone interested in the intellectual and cultural history of the United States. In order of appearance, the essays are: "Jonathan Edwards and the Great Awakening" by John E. Smith "Heart and Head: The Mind of Thomas Jefferson" by Andrew J. Reck"Emerson and the American Future" by Robert C. Pollock"Chauncey Wright and the Pragmatists" by Edward Madden"Charles S. Peirce: Action Through Thought – The Ethics of Experience" by Vincent G. Potter"Life Is in the Transitions’: Radical Empiricism and Contemporary Concerns" by John J. McDermott"John Dewey and the Metaphysics of American Democracy" by Ralph W. Sleeper"Individualization and Unification in Sartre and Dewey" by Thelma Z. Levine"Josiah Royce: Anticipator of European Existentialism and Phenomenology" by Jacqueline Ann K. Kegley"The Transcendence of Materialism and Idealism in American Thought" by John Lachs"C. I. Lewis and the Pragmatic Tradition in American Philosophy" by Sandra Rosenthal"The Social Philosophy of George Herbert Mead" by David Miller"Existence as Transaction: A Whiteheadian Study of Causality" by Elizabeth Kraus. (shrink)

In this chapter, we develop the claim that today, in light of the distributed catastrophe called the Anthropocene, the question of ethics first and foremost becomes a question of economy and energy. Supplementing existing ethical approaches to the question of economy and energy, we offer what we understand to be a more fundamental economical interpretation of the Anthropocene by way of Georges Bataille’s philosophical thought on economy. We will argue that inasmuch as it results from what has come to be (...) known as “the great acceleration”, the Anthropocene can be understood as a consequence of an economic consideration of energy that is oriented towards scarcity and utility, which is to say to Bataille’s “restricted economy”. Additionally, we show how for Bataille, such a ‘restricted’ consideration of energy is an ethical affair, since it misunderstands the constitutive abundance of energy associated with “the general economy”, thereby simultaneously and catastrophically misunderstanding the ethos of human existence in servile terms of labour and efficiency. Finally, we investigate how Bataille’s concept of sovereignty seeks to surpass such servility and efficiency by way of a consideration of energy that is oriented towards expenditure. We offer a reinterpretation of the ethics of sovereignty by confronting it with our contemporary deteriorating oikos inhabited in the Anthropocene. We close by arguing that notwithstanding its irrevocable difficulties, the question of ethics in the Anthropocene must be considered as an energetic ethics of sovereignty. (shrink)

Si son œuvre commence aujourd’hui à faire l’objet d’études d’ensemble, il nous semble aussi possible de saisir toute l’ampleur et la richesse de la philosophie de Georges Canguilhem en s’attachant à l’interprétation qu’il propose des différentes facettes de la pensée de Descartes. Thématique de la liberté créatrice, statut de la technique, fonction du « sentiment », problématique de l’individualité biologique, interrogation sur la pertinence de l’opposition mécanisme-finalité, questionnement sur l’historique de la notion de réflexe, réflexion sur la méthode et prise (...) de position sur l’importance philosophique et morale du Cogito : autant de moments d’un panorama qui permettra de mieux comprendre le Descartes de Canguilhem, et donc, on l’espère, Canguilhem lui-même. (shrink)

George Santayana was not only a poet but also a philosopher whose style, concerns, and even positions drew in his own time and continues to draw in ours the attention of poets and, more broadly, literary authors. He was, in short, a poet's philosopher. In so characterizing Santayana, however, there is no slight of his strictly philosophical achievement. The philosophical finesse with which he treated complex topics is, indeed, nowhere more evident than in his rigorous analysis of poetic utterance. (...) The author of this essay explores Santayana's nuanced account of poetic utterance and, then, interprets Santayana's own literary accomplishments, including his philosophical writings, in light of this account. Given the attention which Angus Kerr-Lawson has paid to the rhetorical strategies and literary qualities of this singular philosopher, it is fitting to contribute such an essay to an issue in his honor. (shrink)

The most effective—indeed, the only—way to make the future different from the past is, in the judgment of pragmatists such as William James, John Dewey, and George Herbert Mead, to remake the present. As Dewey notes, "present activity" is the only phase of human conduct really under our control (MW 14.184). 1 For just this reason, we must be mindful of the past and solicitous about the future as well as attuned to the present: "Memory of the past, observation (...) of the present, foresight of the future are indispensable. But they are indispensable to a present liberation, an enriching growth of action" unfolding in the here and now (MW 14.182). 2 Dewey goes so far as to assert: "We do not use the .. (shrink)